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BDBM423461 WO2006061714-ID-03

SMILES: COC(O)[C@@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1

InChI Key: InChIKey=GYPAMRSUOHRGGS-BCKKPBOXSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423461   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3C-like proteinase (3CL-PRO)


(Human SARS coronavirus (SARS-CoV) (Severe acute re...)		BDBM423461
PNG
(WO2006061714-ID-03)
Show SMILES COC(O)[C@@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1
Show InChI InChI=1S/C24H34N4O6/c1-13(2)10-17(22(30)28-19(24(32)34-4)11-14-8-9-25-21(14)29)27-23(31)18-12-15-16(26-18)6-5-7-20(15)33-3/h5-7,12-14,17,19,24,26,32H,8-11H2,1-4H3,(H,25,29)(H,27,31)(H,28,30)/t14-,17-,19+,24?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
WIPO
n/an/an/an/a 800n/an/an/an/a



Pfizer Inc.



Assay Description
Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...

WIPO (2005)


BindingDB Entry DOI: 10.7270/Q2PV6NRF
More data for this
Ligand-Target Pair