null

SMILES: CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5CCOCC5)cc4)c(F)c3)c2n1

InChI Key: InChIKey=XLTJXYZDXRQARQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM423522 (US10508115, Compound Ie-08) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5CCOCC5)cc4)c(F)c3)c2n1 Show InChI InChI=1S/C28H33FN6O4/c1-2-3-12-38-27-33-25(30)24-26(34-27)35(28(36)32-24)17-19-6-9-23(22(29)15-19)39-21-7-4-18(5-8-21)16-31-20-10-13-37-14-11-20/h4-9,15,20,31H,2-3,10-14,16-17H2,1H3,(H,32,36)(H2,30,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10508115 (2019) BindingDB Entry DOI: 10.7270/Q2K35X2W
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM423522 (US10508115, Compound Ie-08) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5CCOCC5)cc4)c(F)c3)c2n1 Show InChI InChI=1S/C28H33FN6O4/c1-2-3-12-38-27-33-25(30)24-26(34-27)35(28(36)32-24)17-19-6-9-23(22(29)15-19)39-21-7-4-18(5-8-21)16-31-20-10-13-37-14-11-20/h4-9,15,20,31H,2-3,10-14,16-17H2,1H3,(H,32,36)(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...				US Patent US10508115 (2019) BindingDB Entry DOI: 10.7270/Q2K35X2W
					More data for this Ligand-Target Pair