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SMILES: Cc1noc(C)c1-c1cnc2[nH]cc(Cc3ccccc3OC(F)F)c2c1

InChI Key: InChIKey=DGJDTCVXXBPLSC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425167   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-164]


(Homo sapiens (Human))		BDBM425167
PNG
(4-[3-[[2-(difluoro- methoxy)phenyl]methyl]- 1H-pyr...)
Show SMILES Cc1noc(C)c1-c1cnc2[nH]cc(Cc3ccccc3OC(F)F)c2c1
Show InChI InChI=1S/C20H17F2N3O2/c1-11-18(12(2)27-25-11)15-8-16-14(9-23-19(16)24-10-15)7-13-5-3-4-6-17(13)26-20(21)22/h3-6,8-10,20H,7H2,1-2H3,(H,23,24)
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Plexxikon Inc.

US Patent


Assay Description
Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...

US Patent US10519177 (2019)


BindingDB Entry DOI: 10.7270/Q2154KDK
More data for this
Ligand-Target Pair