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SMILES: Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(c1)C(F)F

InChI Key: InChIKey=DBXMFQYUEHMMJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 425351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425351 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(c1)C(F)F Show InChI InChI=1S/C21H19F4N5O/c1-11-18(12(2)31-28-11)14-3-17-19(26-6-14)16(15-7-27-30(9-15)20(22)23)10-29(17)8-13-4-21(24,25)5-13/h3,6-7,9-10,13,20H,4-5,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425351 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(c1)C(F)F Show InChI InChI=1S/C21H19F4N5O/c1-11-18(12(2)31-28-11)14-3-17-19(26-6-14)16(15-7-27-30(9-15)20(22)23)10-29(17)8-13-4-21(24,25)5-13/h3,6-7,9-10,13,20H,4-5,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425351 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(c1)C(F)F Show InChI InChI=1S/C21H19F4N5O/c1-11-18(12(2)31-28-11)14-3-17-19(26-6-14)16(15-7-27-30(9-15)20(22)23)10-29(17)8-13-4-21(24,25)5-13/h3,6-7,9-10,13,20H,4-5,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair