null

SMILES: Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1

InChI Key: InChIKey=ZVROERWTIKLVHP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 425352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425352 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C22H20F5N5O/c1-12-19(13(2)33-30-12)15-3-18-20(28-6-15)17(10-31(18)8-14-4-21(23,24)5-14)16-7-29-32(9-16)11-22(25,26)27/h3,6-7,9-10,14H,4-5,8,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425352 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C22H20F5N5O/c1-12-19(13(2)33-30-12)15-3-18-20(28-6-15)17(10-31(18)8-14-4-21(23,24)5-14)16-7-29-32(9-16)11-22(25,26)27/h3,6-7,9-10,14H,4-5,8,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425352 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C22H20F5N5O/c1-12-19(13(2)33-30-12)15-3-18-20(28-6-15)17(10-31(18)8-14-4-21(23,24)5-14)16-7-29-32(9-16)11-22(25,26)27/h3,6-7,9-10,14H,4-5,8,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425352 (4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C22H20F5N5O/c1-12-19(13(2)33-30-12)15-3-18-20(28-6-15)17(10-31(18)8-14-4-21(23,24)5-14)16-7-29-32(9-16)11-22(25,26)27/h3,6-7,9-10,14H,4-5,8,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair