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SMILES: Cc1noc(C)c1-c1cnc2c(cn(Cc3ncccn3)c2c1)-c1cnn(C)c1

InChI Key: InChIKey=XIHSSWODHBTEJB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425420 (3,5-dimethyl-4-[3-(1-methylpyrazol-4- yl)-1-(pyrim...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(Cc3ncccn3)c2c1)-c1cnn(C)c1 Show InChI InChI=1S/C21H19N7O/c1-13-20(14(2)29-26-13)15-7-18-21(24-8-15)17(16-9-25-27(3)10-16)11-28(18)12-19-22-5-4-6-23-19/h4-11H,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425420 (3,5-dimethyl-4-[3-(1-methylpyrazol-4- yl)-1-(pyrim...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(Cc3ncccn3)c2c1)-c1cnn(C)c1 Show InChI InChI=1S/C21H19N7O/c1-13-20(14(2)29-26-13)15-7-18-21(24-8-15)17(16-9-25-27(3)10-16)11-28(18)12-19-22-5-4-6-23-19/h4-11H,12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair