BindingDB logo
myBDB logout

null

SMILES: Fc1ccc(cc1)-c1nc2c(nccn2c1-c1ccc2[nH]c(=O)[nH]c2c1)N1CCOCC1

InChI Key: InChIKey=FDAWFPURAZCPFT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426072   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor 1


(Homo sapiens (Human))		BDBM426072
PNG
(5-[2-(4-Fluorophenyl)-8-morpholino-imidazo[1,2-a]p...)
Show SMILES Fc1ccc(cc1)-c1nc2c(nccn2c1-c1ccc2[nH]c(=O)[nH]c2c1)N1CCOCC1
Show InChI InChI=1S/C23H19FN6O2/c24-16-4-1-14(2-5-16)19-20(15-3-6-17-18(13-15)27-23(31)26-17)30-8-7-25-21(22(30)28-19)29-9-11-32-12-10-29/h1-8,13H,9-12H2,(H2,26,27,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...

US Patent US10513523 (2019)


BindingDB Entry DOI: 10.7270/Q2KW5JDR
More data for this
Ligand-Target Pair