null

SMILES: C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)ncnc12

InChI Key: InChIKey=HVZTWCPGKZMGJT-YRKGHMEHSA-M

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426318 (US10513534, Compound 406) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H17ClN5O12P3/c1-11(12)7(18)5(2-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(11)17-4-16-6-8(13)14-3-15-9(6)17/h3-5,7,10,18H,2H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/p-1/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426318 (US10513534, Compound 406) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H17ClN5O12P3/c1-11(12)7(18)5(2-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(11)17-4-16-6-8(13)14-3-15-9(6)17/h3-5,7,10,18H,2H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/p-1/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair