BDBM4272 (5-Sulfofurfural)Sodium Salt::Tyrphostin deriv. 2::sodium 5-(2,2-dicyanoeth-1-en-1-yl)furan-2-sulfonate

SMILES: [O-]S(=O)(=O)c1ccc(C=C(C#N)C#N)o1

InChI Key: InChIKey=LLPRRMGWDXUHKP-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4272 ((5-Sulfofurfural)Sodium Salt | Tyrphostin deriv. 2...) Show SMILES [O-]S(=O)(=O)c1ccc(C=C(C#N)C#N)o1 Show InChI InChI=1S/C8H4N2O4S/c9-4-6(5-10)3-7-1-2-8(14-7)15(11,12)13/h1-3H,(H,11,12,13)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	7.6	22
Hebrew University of Jerusalem					Assay Description The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.				J Med Chem 34: 1896-907 (1991) Article DOI: 10.1021/jm00110a022 BindingDB Entry DOI: 10.7270/Q2KW5D7V
					More data for this Ligand-Target Pair