BDBM42898 5-Acetyl-2-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsulfanyl)-acetylamino]-4-methyl-thiophene-3-carboxylic acid ethyl ester::5-acetyl-2-[[2-[(3-cyano-4,6-dimethyl-2-pyridinyl)thio]-1-oxoethyl]amino]-4-methyl-3-thiophenecarboxylic acid ethyl ester::5-acetyl-2-[[2-[(3-cyano-4,6-dimethyl-2-pyridyl)thio]acetyl]amino]-4-methyl-thiophene-3-carboxylic acid ethyl ester::MLS000032460::SMR000001604::cid_656126::ethyl 2-[2-(3-cyano-4,6-dimethyl-pyridin-2-yl)sulfanylethanoylamino]-5-ethanoyl-4-methyl-thiophene-3-carboxylate::ethyl 5-acetyl-2-[[2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanylacetyl]amino]-4-methylthiophene-3-carboxylate

SMILES: CCOC(=O)c1c(C)c(sc1NC(=O)CSc1nc(C)cc(C)c1C#N)C(C)=O

InChI Key: InChIKey=YCGBFDVDPYKINI-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 42898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nuclear receptor coactivator 3 isoform a (Homo sapiens (Human))	BDBM42898 (5-Acetyl-2-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsu...) Show SMILES CCOC(=O)c1c(C)c(sc1NC(=O)CSc1nc(C)cc(C)c1C#N)C(C)=O Show InChI InChI=1S/C20H21N3O4S2/c1-6-27-20(26)16-12(4)17(13(5)24)29-19(16)23-15(25)9-28-18-14(8-21)10(2)7-11(3)22-18/h7H,6,9H2,1-5H3,(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2707ZV7
					More data for this Ligand-Target Pair
nuclear receptor coactivator 1 isoform 1 (Homo sapiens (Human))	BDBM42898 (5-Acetyl-2-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsu...) Show SMILES CCOC(=O)c1c(C)c(sc1NC(=O)CSc1nc(C)cc(C)c1C#N)C(C)=O Show InChI InChI=1S/C20H21N3O4S2/c1-6-27-20(26)16-12(4)17(13(5)24)29-19(16)23-15(25)9-28-18-14(8-21)10(2)7-11(3)22-18/h7H,6,9H2,1-5H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2FT8JGV
					More data for this Ligand-Target Pair
NCOA2 protein (Homo sapiens (Human))	BDBM42898 (5-Acetyl-2-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsu...) Show SMILES CCOC(=O)c1c(C)c(sc1NC(=O)CSc1nc(C)cc(C)c1C#N)C(C)=O Show InChI InChI=1S/C20H21N3O4S2/c1-6-27-20(26)16-12(4)17(13(5)24)29-19(16)23-15(25)9-28-18-14(8-21)10(2)7-11(3)22-18/h7H,6,9H2,1-5H3,(H,23,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QZ28CS
					More data for this Ligand-Target Pair