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SMILES: COc1ccc(c(F)c1)-c1cc(ncc1OCc1ccc(C)nc1)C(N)=O

InChI Key: InChIKey=IZIBSGQPFIKWGL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430153   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)		BDBM430153
PNG
(4-(2-fluoro-4-methoxyphenyl)-5-((6- methylpyridin-...)
Show SMILES COc1ccc(c(F)c1)-c1cc(ncc1OCc1ccc(C)nc1)C(N)=O
Show InChI InChI=1S/C20H18FN3O3/c1-12-3-4-13(9-23-12)11-27-19-10-24-18(20(22)25)8-16(19)15-6-5-14(26-2)7-17(15)21/h3-10H,11H2,1-2H3,(H2,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 216n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...

US Patent US10538491 (2020)


BindingDB Entry DOI: 10.7270/Q2GT5QKF
More data for this
Ligand-Target Pair