BDBM43210 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one::1-(3-nitrophenyl)-3-phenyl-prop-2-yn-1-one::1-(3-nitrophenyl)-3-phenylprop-2-yn-1-one::MLS000532223::SMR000137163::cid_781112
SMILES: [O-][N+](=O)c1cccc(c1)C(=O)C#Cc1ccccc1
InChI Key: InChIKey=JODIUOIVYGKAJH-UHFFFAOYSA-N
Data: 6 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cell division cycle 42 (GTP binding protein, 25kDa) (Homo sapiens (Human)) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q22J698B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Mus musculus) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 2.35E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsf1 protein (Mus musculus) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >2.60E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RPL19A (Saccharomyces cerevisiae) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 7.47E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2JQ0ZGP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
LAP4 (Saccharomyces cerevisiae) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 7.75E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21R6P02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Mus musculus) | BDBM43210 (1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2377749 | |||||||||||
More data for this Ligand-Target Pair |