BDBM4322 (4-Morpholinobenzylidene)malononitrile::2-{[4-(morpholin-4-yl)phenyl]methylidene}propanedinitrile::benzylidenemalononitrile (BMN) deriv. 6::cid_321779
SMILES: N#C\[#6](=[#6]/c1ccc(cc1)-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1)C#N
InChI Key: InChIKey=CHKTYKSOGLZPFK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4322 ((4-Morpholinobenzylidene)malononitrile | 2-{[4-(mo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >2.50E+5 | >-4.86 | >6.25E+5 | n/a | n/a | n/a | n/a | 7.6 | 22 |
Hebrew University of Jerusalem | Assay Description The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate. | J Med Chem 32: 2344-52 (1989) Article DOI: 10.1021/jm00130a020 BindingDB Entry DOI: 10.7270/Q2G44NHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans) | BDBM4322 ((4-Morpholinobenzylidene)malononitrile | 2-{[4-(mo...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
POsterior Segregation family member (pos-1) (Caenorhabditis elegans) | BDBM4322 ((4-Morpholinobenzylidene)malononitrile | 2-{[4-(mo...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C | |||||||||||
More data for this Ligand-Target Pair |