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SMILES: CC1(CN)CCN(CC1)c1ncc(Sc2cccc(NC(=O)c3c(O)nc4cnccn4c3=O)c2Cl)[nH]c1=O

InChI Key: InChIKey=DUPWOUARKMOUAI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433300   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 11


(Homo sapiens (Human))		BDBM433300
PNG
(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Show SMILES CC1(CN)CCN(CC1)c1ncc(Sc2cccc(NC(=O)c3c(O)nc4cnccn4c3=O)c2Cl)[nH]c1=O
Show InChI InChI=1S/C25H25ClN8O4S/c1-25(13-27)5-8-33(9-6-25)20-23(37)32-17(12-29-20)39-15-4-2-3-14(19(15)26)30-21(35)18-22(36)31-16-11-28-7-10-34(16)24(18)38/h2-4,7,10-12,36H,5-6,8-9,13,27H2,1H3,(H,30,35)(H,32,37)
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US Patent
n/an/a<50n/an/an/an/an/an/a



SYNBLia Therapeutics, Inc.

US Patent


Assay Description
IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...

US Patent US10561655 (2020)


BindingDB Entry DOI: 10.7270/Q23F4S2Z
More data for this
Ligand-Target Pair