null
SMILES: COc1cccc(SCCNCC2(F)CCN(CC2)C(=O)c2ccc(F)c(Cl)c2)c1
InChI Key: InChIKey=WZKXISBZTZAMNX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM433516 (US10562853, Compound 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE US Patent | Assay Description 5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie... | US Patent US10562853 (2020) BindingDB Entry DOI: 10.7270/Q29Z979D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM433516 (US10562853, Compound 39) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE US Patent | Assay Description Alpha1-adrenergic Receptor: Radioligand binding was performed using tissue (rat cortex). All assays were carried out in duplicates. 50 μL workin... | US Patent US10562853 (2020) BindingDB Entry DOI: 10.7270/Q29Z979D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM433516 (US10562853, Compound 39) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE US Patent | Assay Description D2 Dopamine Receptor:Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human D2 receptor. All assays we... | US Patent US10562853 (2020) BindingDB Entry DOI: 10.7270/Q29Z979D | |||||||||||
More data for this Ligand-Target Pair |