Found 10 hits for monomerid = 433528 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.117 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
| Assay Description 5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie... |
US Patent US10562853 (2020)
BindingDB Entry DOI: 10.7270/Q29Z979D |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
| Assay Description Alpha1-adrenergic Receptor: Radioligand binding was performed using tissue (rat cortex). All assays were carried out in duplicates. 50 μL workin... |
US Patent US10562853 (2020)
BindingDB Entry DOI: 10.7270/Q29Z979D |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 912 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
| Assay Description D2 Dopamine Receptor:Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human D2 receptor. All assays we... |
US Patent US10562853 (2020)
BindingDB Entry DOI: 10.7270/Q29Z979D |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 102 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM433528
(US10562853, Compound 51)Show SMILES CNc1ccccc1OCCNCC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C22H26ClF2N3O2/c1-26-19-4-2-3-5-20(19)30-13-10-27-15-22(25)8-11-28(12-9-22)21(29)16-6-7-18(24)17(23)14-16/h2-7,14,26-27H,8-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 162 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |