BDBM43435 1'-{[5-(hydroxymethyl)-2-furyl]methyl}-N-(2-phenylethyl)-1,4'-bipiperidine-4-carboxamide::1-[1-[(5-methylol-2-furyl)methyl]-4-piperidyl]-N-phenethyl-isonipecotamide::1-[1-[[5-(hydroxymethyl)-2-furanyl]methyl]-4-piperidinyl]-N-(2-phenylethyl)-4-piperidinecarboxamide::1-[1-[[5-(hydroxymethyl)furan-2-yl]methyl]piperidin-4-yl]-N-(2-phenylethyl)piperidine-4-carboxamide::MLS000732998::SMR000317864::cid_16187723

SMILES: OCc1ccc(CN2CCC(CC2)N2CCC(CC2)C(=O)NCCc2ccccc2)o1

InChI Key: InChIKey=BHGAPAGMWUFIJJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 43435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43435 (1'-{[5-(hydroxymethyl)-2-furyl]methyl}-N-(2-ph...) Show SMILES OCc1ccc(CN2CCC(CC2)N2CCC(CC2)C(=O)NCCc2ccccc2)o1 Show InChI InChI=1S/C25H35N3O3/c29-19-24-7-6-23(31-24)18-27-14-11-22(12-15-27)28-16-9-21(10-17-28)25(30)26-13-8-20-4-2-1-3-5-20/h1-7,21-22,29H,8-19H2,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.27E+6	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair