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null

SMILES: Nc1cc(C2CCNCc3cccc(OCc4cccc(Cn5cc2cn5)c4)c3)c2nn[nH]c2n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 434851
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM434851 (7-{17-Oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen Cat. #A12222) which can...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM434851 (7-{17-Oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM434851 (7-{17-Oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen Cat. ...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair