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SMILES: O=C1NCC(N1c1ccc2[nH]cnc2c1)c1ccc(cc1)-c1nccs1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM435072 (US10584120, Compound 1) Show SMILES O=C1NCC(N1c1ccc2[nH]cnc2c1)c1ccc(cc1)-c1nccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes; Academia Sinica US Patent					Assay Description An inhibition activity assay of QC inhibitors was conducted. See Huang et al., J. Biol. Chem. 2011, 286, 12439-12449. A reaction mixture containing 3...				US Patent US10584120 (2020) BindingDB Entry DOI: 10.7270/Q2ZK5K20
					More data for this Ligand-Target Pair