null

SMILES: C[C@@]1(O)[C@@H](COc2ccc3ccc(N)nc3c2)O[C@H]([C@@H]1O)n1ccc2c(N)ncnc12

InChI Key: InChIKey=LITUSLGKCXVKPY-ZHFAOOELSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM435509 ((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES C[C@@]1(O)[C@@H](COc2ccc3ccc(N)nc3c2)O[C@H]([C@@H]1O)n1ccc2c(N)ncnc12 |r| Show InChI InChI=1S/C21H22N6O4/c1-21(29)15(9-30-12-4-2-11-3-5-16(22)26-14(11)8-12)31-20(17(21)28)27-7-6-13-18(23)24-10-25-19(13)27/h2-8,10,15,17,20,28-29H,9H2,1H3,(H2,22,26)(H2,23,24,25)/t15-,17+,20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Prelude Therapeutics Incorporated US Patent					Assay Description Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...				US Patent US10570140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1GTT
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM435509 ((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES C[C@@]1(O)[C@@H](COc2ccc3ccc(N)nc3c2)O[C@H]([C@@H]1O)n1ccc2c(N)ncnc12 |r| Show InChI InChI=1S/C21H22N6O4/c1-21(29)15(9-30-12-4-2-11-3-5-16(22)26-14(11)8-12)31-20(17(21)28)27-7-6-13-18(23)24-10-25-19(13)27/h2-8,10,15,17,20,28-29H,9H2,1H3,(H2,22,26)(H2,23,24,25)/t15-,17+,20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM435509 ((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES C[C@@]1(O)[C@@H](COc2ccc3ccc(N)nc3c2)O[C@H]([C@@H]1O)n1ccc2c(N)ncnc12 |r| Show InChI InChI=1S/C21H22N6O4/c1-21(29)15(9-30-12-4-2-11-3-5-16(22)26-14(11)8-12)31-20(17(21)28)27-7-6-13-18(23)24-10-25-19(13)27/h2-8,10,15,17,20,28-29H,9H2,1H3,(H2,22,26)(H2,23,24,25)/t15-,17+,20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair