null

SMILES: CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(O)ncc2C1=O)c1ccccc1

InChI Key: InChIKey=MFVCDOIXYGRALQ-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 436430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436430 ((R)-2-hydroxy-9- methyl-6-(3-((3- (methylamino)-1-...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(O)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c1-26-12-11-22(19-8-4-3-5-9-19)33-17-18-7-6-10-20(15-18)30-14-13-29(2)23-21(24(30)31)16-27-25(32)28-23/h3-10,15-16,22,26H,11-14,17H2,1-2H3,(H,27,28,32)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM436430 ((R)-2-hydroxy-9- methyl-6-(3-((3- (methylamino)-1-...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(O)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c1-26-12-11-22(19-8-4-3-5-9-19)33-17-18-7-6-10-20(15-18)30-14-13-29(2)23-21(24(30)31)16-27-25(32)28-23/h3-10,15-16,22,26H,11-14,17H2,1-2H3,(H,27,28,32)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description NET: Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer co...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436430 ((R)-2-hydroxy-9- methyl-6-(3-((3- (methylamino)-1-...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(O)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c1-26-12-11-22(19-8-4-3-5-9-19)33-17-18-7-6-10-20(15-18)30-14-13-29(2)23-21(24(30)31)16-27-25(32)28-23/h3-10,15-16,22,26H,11-14,17H2,1-2H3,(H,27,28,32)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair