null

SMILES: CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(ncc3C2=O)N(C)C)cc1)c1cccs1

InChI Key: InChIKey=CMVIUAMERNJGJV-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 436608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436608 ((S)-8- (dimethylamino)-1- methyl-4-(4-(3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(ncc3C2=O)N(C)C)cc1)c1cccs1 |r| Show InChI InChI=1S/C26H33N5O2S/c1-27-12-11-23(24-6-5-15-34-24)33-20-9-7-19(8-10-20)18-31-14-13-30(4)22-16-25(29(2)3)28-17-21(22)26(31)32/h5-10,15-17,23,27H,11-14,18H2,1-4H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436608 ((S)-8- (dimethylamino)-1- methyl-4-(4-(3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(ncc3C2=O)N(C)C)cc1)c1cccs1 |r| Show InChI InChI=1S/C26H33N5O2S/c1-27-12-11-23(24-6-5-15-34-24)33-20-9-7-19(8-10-20)18-31-14-13-30(4)22-16-25(29(2)3)28-17-21(22)26(31)32/h5-10,15-17,23,27H,11-14,18H2,1-4H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM436608 ((S)-8- (dimethylamino)-1- methyl-4-(4-(3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(ncc3C2=O)N(C)C)cc1)c1cccs1 |r| Show InChI InChI=1S/C26H33N5O2S/c1-27-12-11-23(24-6-5-15-34-24)33-20-9-7-19(8-10-20)18-31-14-13-30(4)22-16-25(29(2)3)28-17-21(22)26(31)32/h5-10,15-17,23,27H,11-14,18H2,1-4H3/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description NET: Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer co...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair