BDBM43827 (E)-3-(1-benzyl-3-phenyl-pyrazol-4-yl)acrylic acid::(E)-3-(1-benzyl-3-phenylpyrazol-4-yl)prop-2-enoic acid::(E)-3-[3-phenyl-1-(phenylmethyl)-4-pyrazolyl]-2-propenoic acid::(E)-3-[3-phenyl-1-(phenylmethyl)pyrazol-4-yl]prop-2-enoic acid::Aminoglycosides, 4::MLS000567315::SMR000154054::cid_2565969

SMILES: OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1ccccc1

InChI Key: InChIKey=LTHZEHAKKYOLNA-VAWYXSNFSA-N

Data: 1 IC50  1 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 43827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
electroneutral potassium-chloride cotransporter KCC2 (Homo sapiens (Human))	BDBM43827 ((E)-3-(1-benzyl-3-phenyl-pyrazol-4-yl)acrylic acid...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-18(23)12-11-17-14-21(13-15-7-3-1-4-8-15)20-19(17)16-9-5-2-6-10-16/h1-12,14H,13H2,(H,22,23)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.37E+7	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q52N1X
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM43827 ((E)-3-(1-benzyl-3-phenyl-pyrazol-4-yl)acrylic acid...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-18(23)12-11-17-14-21(13-15-7-3-1-4-8-15)20-19(17)16-9-5-2-6-10-16/h1-12,14H,13H2,(H,22,23)/b12-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BV7F1T
					More data for this Ligand-Target Pair
electroneutral potassium-chloride cotransporter KCC2 (Homo sapiens (Human))	BDBM43827 ((E)-3-(1-benzyl-3-phenyl-pyrazol-4-yl)acrylic acid...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-18(23)12-11-17-14-21(13-15-7-3-1-4-8-15)20-19(17)16-9-5-2-6-10-16/h1-12,14H,13H2,(H,22,23)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.77E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TX3CSC
					More data for this Ligand-Target Pair
Aminoacyl-tRNA synthetase (Thermus thermophilus)	BDBM43827 ((E)-3-(1-benzyl-3-phenyl-pyrazol-4-yl)acrylic acid...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-18(23)12-11-17-14-21(13-15-7-3-1-4-8-15)20-19(17)16-9-5-2-6-10-16/h1-12,14H,13H2,(H,22,23)/b12-11+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.70E+6	n/a	n/a	n/a	7.5	0
Wayne State University					Assay Description Binding assay of Aminoglycoside antibiotics and kanamycin A derivatives for the bacterial A site RNA.				Chem Biol 9: 455-63 (2002) Article DOI: 10.1016/S1074-5521(02)00125-4 BindingDB Entry DOI: 10.7270/Q2R49P66
					More data for this Ligand-Target Pair