null

SMILES: F[C@H]1CNCCC1Nc1cncc(n1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1

InChI Key: InChIKey=MUBJROZPDFWDIB-ZENAZSQFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442933 (US10653688, Compound 111) Show SMILES F[C@H]1CNCCC1Nc1cncc(n1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1 |r| Show InChI InChI=1S/C22H23FN6O/c23-17-10-24-6-5-18(17)27-21-12-25-11-19(28-21)14-3-4-15-9-26-20(8-16(15)7-14)29-22(30)13-1-2-13/h3-4,7-9,11-13,17-18,24H,1-2,5-6,10H2,(H,27,28)(H,26,29,30)/t17-,18?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442933 (US10653688, Compound 111) Show SMILES F[C@H]1CNCCC1Nc1cncc(n1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1 |r| Show InChI InChI=1S/C22H23FN6O/c23-17-10-24-6-5-18(17)27-21-12-25-11-19(28-21)14-3-4-15-9-26-20(8-16(15)7-14)29-22(30)13-1-2-13/h3-4,7-9,11-13,17-18,24H,1-2,5-6,10H2,(H,27,28)(H,26,29,30)/t17-,18?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020)
					More data for this Ligand-Target Pair