BDBM444471 US10662159, Example 61

SMILES: Fc1cncc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1

InChI Key: InChIKey=FPNBRHOFNHNGQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444471 (US10662159, Example 61) Show SMILES Fc1cncc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C16H15F7N2O3/c17-9-3-11(6-24-5-9)27-10-1-2-14(4-10)7-25(8-14)13(26)28-12(15(18,19)20)16(21,22)23/h3,5-6,10,12H,1-2,4,7-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020)
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