null

SMILES: Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccnc(CO)c1)-c1ccccc1

InChI Key: InChIKey=PMRXIUUXGGEYOQ-GGXMVOPNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445331 (US10669239, Compound 56 | US10927079, Compound 56) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccnc(CO)c1)-c1ccccc1 |r| Show InChI InChI=1S/C31H30F2N4O3/c1-17-11-25(28(18-7-5-4-6-8-18)36-27(17)19-9-10-34-20(12-19)16-38)35-30(40)37-29-21-13-23(32)24(33)14-22(21)31(2,3)15-26(29)39/h4-14,26,29,38-39H,15-16H2,1-3H3,(H2,35,37,40)/t26-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021) BindingDB Entry DOI: 10.7270/Q2988B3P
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445331 (US10669239, Compound 56 | US10927079, Compound 56) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccnc(CO)c1)-c1ccccc1 |r| Show InChI InChI=1S/C31H30F2N4O3/c1-17-11-25(28(18-7-5-4-6-8-18)36-27(17)19-9-10-34-20(12-19)16-38)35-30(40)37-29-21-13-23(32)24(33)14-22(21)31(2,3)15-26(29)39/h4-14,26,29,38-39H,15-16H2,1-3H3,(H2,35,37,40)/t26-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair