BDBM446784 (1R,2R,3R,5R,6R)-2-amino-3-[(6-chloropyridin-2- yl)methoxy]-6-fluorobicyclo[3.0.1]hexane-2,6- dicarboxylic acid::US10689327, Compound (II)-8

SMILES: N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(Cl)n1)[C@]2(F)C(O)=O)C(O)=O

InChI Key: InChIKey=FUOXGTLPOUSBMV-IAHPCQQPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM446784 ((1R,2R,3R,5R,6R)-2-amino-3-[(6-chloropyridin-2- yl...) Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(Cl)n1)[C@]2(F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H14ClFN2O5/c15-9-3-1-2-6(18-9)5-23-8-4-7-10(13(7,16)11(19)20)14(8,17)12(21)22/h1-3,7-8,10H,4-5,17H2,(H,19,20)(H,21,22)/t7-,8-,10+,13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...				US Patent US10689327 (2020)
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM446784 ((1R,2R,3R,5R,6R)-2-amino-3-[(6-chloropyridin-2- yl...) Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(Cl)n1)[C@]2(F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H14ClFN2O5/c15-9-3-1-2-6(18-9)5-23-8-4-7-10(13(7,16)11(19)20)14(8,17)12(21)22/h1-3,7-8,10H,4-5,17H2,(H,19,20)(H,21,22)/t7-,8-,10+,13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.3	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...				US Patent US10689327 (2020)
					More data for this Ligand-Target Pair