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SMILES: Clc1ccc(N2CCN(Cc3cocn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1

InChI Key: InChIKey=STOGHDINYGFDGP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448674   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
SRSF protein kinase 1


(Homo sapiens (Human))		BDBM448674
PNG
(N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl...)
Show SMILES Clc1ccc(N2CCN(Cc3cocn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1
Show InChI InChI=1S/C24H22ClN5O3/c25-18-1-2-21(30-11-9-29(10-12-30)14-19-15-32-16-27-19)20(13-18)28-24(31)23-4-3-22(33-23)17-5-7-26-8-6-17/h1-8,13,15-16H,9-12,14H2,(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.20n/an/an/an/an/an/a



Exonate Limited

US Patent


Assay Description
Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...

US Patent US10696661 (2020)


BindingDB Entry DOI: 10.7270/Q23B635R
More data for this
Ligand-Target Pair