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SMILES: CP(C)(=O)c1ccccc1-c1ccc(N2[C@H](CO)C[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F

InChI Key: InChIKey=OPZVDTKNGXMQLL-MGPUTAFESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450349 (US10676431, Example 112 | US11117861, Example 112) Show SMILES CP(C)(=O)c1ccccc1-c1ccc(N2[C@H](CO)C[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C26H24ClF3N3O4P/c1-38(2,37)22-6-4-3-5-16(22)17-8-10-21(24(30)23(17)29)33-15(13-34)12-20(25(33)35)32-26(36)31-19-9-7-14(27)11-18(19)28/h3-11,15,20,34H,12-13H2,1-2H3,(H2,31,32,36)/t15-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.270	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450349 (US10676431, Example 112 | US11117861, Example 112) Show SMILES CP(C)(=O)c1ccccc1-c1ccc(N2[C@H](CO)C[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C26H24ClF3N3O4P/c1-38(2,37)22-6-4-3-5-16(22)17-8-10-21(24(30)23(17)29)33-15(13-34)12-20(25(33)35)32-26(36)31-19-9-7-14(27)11-18(19)28/h3-11,15,20,34H,12-13H2,1-2H3,(H2,31,32,36)/t15-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450349 (US10676431, Example 112 | US11117861, Example 112) Show SMILES CP(C)(=O)c1ccccc1-c1ccc(N2[C@H](CO)C[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C26H24ClF3N3O4P/c1-38(2,37)22-6-4-3-5-16(22)17-8-10-21(24(30)23(17)29)33-15(13-34)12-20(25(33)35)32-26(36)31-19-9-7-14(27)11-18(19)28/h3-11,15,20,34H,12-13H2,1-2H3,(H2,31,32,36)/t15-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	0.270	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450349 (US10676431, Example 112 | US11117861, Example 112) Show SMILES CP(C)(=O)c1ccccc1-c1ccc(N2[C@H](CO)C[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C26H24ClF3N3O4P/c1-38(2,37)22-6-4-3-5-16(22)17-8-10-21(24(30)23(17)29)33-15(13-34)12-20(25(33)35)32-26(36)31-19-9-7-14(27)11-18(19)28/h3-11,15,20,34H,12-13H2,1-2H3,(H2,31,32,36)/t15-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair