null

SMILES: Nc1ncnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCCc2cc(F)c(F)cc12

InChI Key: InChIKey=NRHGITZZOBOACN-IPXJXJKCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 453011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM453011 ((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES Nc1ncnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCCc2cc(F)c(F)cc12 |r| Show InChI InChI=1S/C19H18F2N4O4/c20-11-5-8-2-4-28-15(10(8)6-12(11)21)16-13(26)14(27)19(29-16)25-3-1-9-17(22)23-7-24-18(9)25/h1,3,5-7,13-16,19,26-27H,2,4H2,(H2,22,23,24)/t13-,14+,15+,16-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.45	n/a	n/a	n/a	n/a	n/a	n/a
Prelude Therapeutics Incorporated US Patent					Assay Description Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...				US Patent US10711007 (2020) BindingDB Entry DOI: 10.7270/Q2RR2286
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM453011 ((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES Nc1ncnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCCc2cc(F)c(F)cc12 |r| Show InChI InChI=1S/C19H18F2N4O4/c20-11-5-8-2-4-28-15(10(8)6-12(11)21)16-13(26)14(27)19(29-16)25-3-1-9-17(22)23-7-24-18(9)25/h1,3,5-7,13-16,19,26-27H,2,4H2,(H2,22,23,24)/t13-,14+,15+,16-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KS6VR9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM453011 ((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...) Show SMILES Nc1ncnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCCc2cc(F)c(F)cc12 |r| Show InChI InChI=1S/C19H18F2N4O4/c20-11-5-8-2-4-28-15(10(8)6-12(11)21)16-13(26)14(27)19(29-16)25-3-1-9-17(22)23-7-24-18(9)25/h1,3,5-7,13-16,19,26-27H,2,4H2,(H2,22,23,24)/t13-,14+,15+,16-,19+/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FJ2M0C
					More data for this Ligand-Target Pair