null

SMILES: CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1

InChI Key: InChIKey=XEFZVZBFRMDJOZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Putative sugar transporter (Plasmodium falciparum)	BDBM453234 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrido[3...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1 Show InChI InChI=1S/C27H25N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-15-28-11-10-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-15,17H,16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453234 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrido[3...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1 Show InChI InChI=1S/C27H25N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-15-28-11-10-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-15,17H,16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair