null

SMILES: CC(=O)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC2CCCC2)c1

InChI Key: InChIKey=DGOOAGUUOQIOQU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Putative sugar transporter (Plasmodium falciparum)	BDBM453272 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...) Show SMILES CC(=O)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC2CCCC2)c1 Show InChI InChI=1S/C31H33N7O3/c1-20(39)38-14-13-28-27(18-38)31(35-25-11-9-21(10-12-25)23-16-32-33-17-23)37-30(36-28)22-5-4-8-26(15-22)41-19-29(40)34-24-6-2-3-7-24/h4-5,8-12,15-17,24H,2-3,6-7,13-14,18-19H2,1H3,(H,32,33)(H,34,40)(H,35,36,37)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453272 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...) Show SMILES CC(=O)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC2CCCC2)c1 Show InChI InChI=1S/C31H33N7O3/c1-20(39)38-14-13-28-27(18-38)31(35-25-11-9-21(10-12-25)23-16-32-33-17-23)37-30(36-28)22-5-4-8-26(15-22)41-19-29(40)34-24-6-2-3-7-24/h4-5,8-12,15-17,24H,2-3,6-7,13-14,18-19H2,1H3,(H,32,33)(H,34,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair