BDBM453276 US10729710, Compound (Ia)
SMILES: CCCN1CCC[C@@H]2CC3=C(CCCC3=O)C[C@@H]12
InChI Key: InChIKey=QLIKRYHBUISCTR-UKRRQHHQSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM453276 (US10729710, Compound (Ia)) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is... | US Patent US10729710 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM453276 (US10729710, Compound (Ia)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >6.00E+3 | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description Evaluation of the agonist activity of compounds (I), (Ia) and (Ib) at the human 5-HT2B receptor was performed by Eurofins/Cerep (France) measuring th... | US Patent US10729710 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM453276 (US10729710, Compound (Ia)) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ... | US Patent US10729710 (2020) | |||||||||||
More data for this Ligand-Target Pair |