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SMILES: CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN

InChI Key: InChIKey=GIOPVJWOYZBTNW-NVMNQCDNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 454365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454365 (US10717734, Compound 41) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H29FN4O2S/c1-15(2)23-19(12-17-7-8-21(27-13-17)31(29,30)16(3)4)22-20(6-5-11-26-22)28(23)14-18(24)9-10-25/h5-9,11,13,15-16H,10,12,14,25H2,1-4H3/b18-9-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM454365 (US10717734, Compound 41) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H29FN4O2S/c1-15(2)23-19(12-17-7-8-21(27-13-17)31(29,30)16(3)4)22-20(6-5-11-26-22)28(23)14-18(24)9-10-25/h5-9,11,13,15-16H,10,12,14,25H2,1-4H3/b18-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM454365 (US10717734, Compound 41) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H29FN4O2S/c1-15(2)23-19(12-17-7-8-21(27-13-17)31(29,30)16(3)4)22-20(6-5-11-26-22)28(23)14-18(24)9-10-25/h5-9,11,13,15-16H,10,12,14,25H2,1-4H3/b18-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454365 (US10717734, Compound 41) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H29FN4O2S/c1-15(2)23-19(12-17-7-8-21(27-13-17)31(29,30)16(3)4)22-20(6-5-11-26-22)28(23)14-18(24)9-10-25/h5-9,11,13,15-16H,10,12,14,25H2,1-4H3/b18-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair