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SMILES: CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C2CC2)c2ncccc2n1C\C(F)=C\CN

InChI Key: InChIKey=GVILXUAFGOZZHX-MFOYZWKCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454368 (US10717734, Compound 44) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C2CC2)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H27FN4O2S/c1-15(2)23-19(12-16-5-8-21(27-13-16)31(29,30)18-6-7-18)22-20(4-3-11-26-22)28(23)14-17(24)9-10-25/h3-5,8-9,11,13,15,18H,6-7,10,12,14,25H2,1-2H3/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454368 (US10717734, Compound 44) Show SMILES CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C2CC2)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C23H27FN4O2S/c1-15(2)23-19(12-16-5-8-21(27-13-16)31(29,30)18-6-7-18)22-20(4-3-11-26-22)28(23)14-17(24)9-10-25/h3-5,8-9,11,13,15,18H,6-7,10,12,14,25H2,1-2H3/b17-9-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair