BDBM454981 US10730870, Example 208

SMILES: COc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C

InChI Key: InChIKey=DRLPBXWROOXNQA-XQBPLPMBSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM454981 (US10730870, Example 208) Show SMILES COc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C25H30N4O5S/c1-14(2)22(20-10-21(33-4)28-34-20)25(32)29-12-18(30)9-19(29)24(31)26-11-16-5-7-17(8-6-16)23-15(3)27-13-35-23/h5-8,10,13-14,18-19,22,30H,9,11-12H2,1-4H3,(H,26,31)/t18-,19+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
ARVINAS OPERATIONS, INC.; YALE UNIVERSITY US Patent					Assay Description The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). His-tagged VHL protein was immobilized on a carboxym...				US Patent US10730870 (2020)
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