BDBM456492 US10723742, Example 219

SMILES: CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1

InChI Key: InChIKey=BFDGZKLKOKNYDI-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456492 (US10723742, Example 219) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C30H29ClF2N6O2/c1-3-30(41,4-2)16-39-28-25(36-37-39)13-23(27(33)26(28)31)21-8-7-18(29(40)38-10-9-20(35)15-38)11-22(21)17-5-6-19(14-34)24(32)12-17/h5-8,11-13,20,41H,3-4,9-10,15-16,35H2,1-2H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020)
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