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SMILES: OC(=O)CC[C@H](NC(=O)NCCSCc1ccc(I)cc1)C(O)=O

InChI Key: InChIKey=IZMSXSFDVSUCIT-LBPRGKRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456923   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM456923
PNG
(US10736974, Compound DCIBC)
Show SMILES OC(=O)CC[C@H](NC(=O)NCCSCc1ccc(I)cc1)C(O)=O |r|
Show InChI InChI=1S/C15H19IN2O5S/c16-11-3-1-10(2-4-11)9-24-8-7-17-15(23)18-12(14(21)22)5-6-13(19)20/h1-4,12H,5-9H2,(H,19,20)(H,21,22)(H2,17,18,23)/t12-/m0/s1
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US Patent
 0.0300n/an/an/an/an/an/an/an/a



THE JOHNS HOPKINS UNIVERSITY

US Patent


Assay Description
The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...

US Patent US10736974 (2020)


BindingDB Entry DOI: 10.7270/Q29C71GJ
More data for this
Ligand-Target Pair