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SMILES: Cc1[nH]c2c(c(nn2c(=O)c1-c1nnc(o1)N1CCCCC1CN)C(F)(F)F)-c1ccccc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457623   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclic GMP-AMP synthase [155-522]


(Homo sapiens (Human))		BDBM457623
PNG
(US10738056, Compound D1070)
Show SMILES Cc1[nH]c2c(c(nn2c(=O)c1-c1nnc(o1)N1CCCCC1CN)C(F)(F)F)-c1ccccc1
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PC cid
PC sid
UniChem
US Patent
n/an/a<20n/an/an/an/an/an/a



Aduro BioTech Inc.

US Patent


Assay Description
Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...

US Patent US10738056 (2020)


BindingDB Entry DOI: 10.7270/Q28G8PR3
More data for this
Ligand-Target Pair