null

SMILES: O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3cnc(cc23)-c2cncc(N1)c2

InChI Key: InChIKey=WWEJNRUKFYYOGK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM459185 (US10759799, Compound 6) Show SMILES O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3cnc(cc23)-c2cncc(N1)c2 Show InChI InChI=1S/C27H19N7O/c35-24-8-7-15-3-1-4-16(9-15)19-5-2-6-21-25(19)32-27(31-21)26-20-11-22(29-14-23(20)33-34-26)17-10-18(30-24)13-28-12-17/h1-6,9-14H,7-8H2,(H,30,35)(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459185 (US10759799, Compound 6) Show SMILES O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3cnc(cc23)-c2cncc(N1)c2 Show InChI InChI=1S/C27H19N7O/c35-24-8-7-15-3-1-4-16(9-15)19-5-2-6-21-25(19)32-27(31-21)26-20-11-22(29-14-23(20)33-34-26)17-10-18(30-24)13-28-12-17/h1-6,9-14H,7-8H2,(H,30,35)(H,31,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair