BDBM459186 US10759799, Compound 7

SMILES: O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(nc23)-c2cncc(N1)c2

InChI Key: InChIKey=HYCOZWOXXFEZLZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM459186 (US10759799, Compound 7) Show SMILES O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(nc23)-c2cncc(N1)c2 Show InChI InChI=1S/C27H19N7O/c35-23-10-7-15-3-1-4-16(11-15)19-5-2-6-21-24(19)32-27(31-21)26-25-22(33-34-26)9-8-20(30-25)17-12-18(29-23)14-28-13-17/h1-6,8-9,11-14H,7,10H2,(H,29,35)(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459186 (US10759799, Compound 7) Show SMILES O=C1CCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(nc23)-c2cncc(N1)c2 Show InChI InChI=1S/C27H19N7O/c35-23-10-7-15-3-1-4-16(11-15)19-5-2-6-21-24(19)32-27(31-21)26-25-22(33-34-26)9-8-20(30-25)17-12-18(29-23)14-28-13-17/h1-6,8-9,11-14H,7,10H2,(H,29,35)(H,31,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair