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SMILES: CN1Cc2c(cnn2C)-c2ccc3[nH]nc(-c4nc5c(cccc5[nH]4)-c4cccc(C1)c4)c3c2

InChI Key: InChIKey=MURDNBFVOLGBQI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM459191 (US10759799, Compound 29) Show SMILES CN1Cc2c(cnn2C)-c2ccc3[nH]nc(-c4nc5c(cccc5[nH]4)-c4cccc(C1)c4)c3c2 Show InChI InChI=1S/C27H23N7/c1-33-14-16-5-3-6-17(11-16)19-7-4-8-23-25(19)30-27(29-23)26-20-12-18(9-10-22(20)31-32-26)21-13-28-34(2)24(21)15-33/h3-13H,14-15H2,1-2H3,(H,29,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459191 (US10759799, Compound 29) Show SMILES CN1Cc2c(cnn2C)-c2ccc3[nH]nc(-c4nc5c(cccc5[nH]4)-c4cccc(C1)c4)c3c2 Show InChI InChI=1S/C27H23N7/c1-33-14-16-5-3-6-17(11-16)19-7-4-8-23-25(19)30-27(29-23)26-20-12-18(9-10-22(20)31-32-26)21-13-28-34(2)24(21)15-33/h3-13H,14-15H2,1-2H3,(H,29,30)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	412	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair