BDBM459197 US10759799, Compound 71

SMILES: O=C1CCCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(N1)c2

InChI Key: InChIKey=UORHOTGTEJJIKC-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM459197 (US10759799, Compound 71) Show SMILES O=C1CCCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(N1)c2 Show InChI InChI=1S/C29H22N6O/c36-26-9-2-5-17-4-1-6-19(12-17)22-7-3-8-25-27(22)33-29(32-25)28-23-14-18(10-11-24(23)34-35-28)20-13-21(31-26)16-30-15-20/h1,3-4,6-8,10-16H,2,5,9H2,(H,31,36)(H,32,33)(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459197 (US10759799, Compound 71) Show SMILES O=C1CCCc2cccc(c2)-c2cccc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(N1)c2 Show InChI InChI=1S/C29H22N6O/c36-26-9-2-5-17-4-1-6-19(12-17)22-7-3-8-25-27(22)33-29(32-25)28-23-14-18(10-11-24(23)34-35-28)20-13-21(31-26)16-30-15-20/h1,3-4,6-8,10-16H,2,5,9H2,(H,31,36)(H,32,33)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020)
					More data for this Ligand-Target Pair