null

SMILES: CC(C)n1n(-c2cccc(N=S(C)(C)=O)n2)c2nc(Nc3ccc(cc3)N(C)C)ncc2c1=O

InChI Key: InChIKey=HOFYXPQFSOEASK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Wee1-like protein kinase (Homo sapiens (Human))	BDBM462344 (US10766902, Example 58) Show SMILES CC(C)n1n(-c2cccc(N=S(C)(C)=O)n2)c2nc(Nc3ccc(cc3)N(C)C)ncc2c1=O Show InChI InChI=1S/C23H28N8O2S/c1-15(2)30-22(32)18-14-24-23(25-16-10-12-17(13-11-16)29(3)4)27-21(18)31(30)20-9-7-8-19(26-20)28-34(5,6)33/h7-15H,1-6H3,(H,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
ALMAC DISCOVERY LIMITED US Patent					Assay Description All reactions took place in 60 μL volumes in reaction buffer containing 40 mM Tris-HCl and 20 mM magnesium chloride, supplemented with 0.1 mg/mL...				US Patent US10766902 (2020)
					More data for this Ligand-Target Pair