BDBM46298 2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[(3-methylbenzylidene)amino]amino]ethanol::2-[(1,1-dioxo-1,2-benzothiazol-3-yl)-[(3-methylphenyl)methylideneamino]amino]ethanol::2-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]-[(3-methylphenyl)methylideneamino]amino]ethanol::3-methylbenzaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(2-hydroxyethyl)hydrazone::MLS000686259::SMR000313102::cid_4421869

SMILES: Cc1cccc(C=NN(CCO)C2=NS(=O)(=O)c3ccccc23)c1

InChI Key: InChIKey=HCCITIBPMUACOB-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 46298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
glutathione S-transferase (Homo sapiens (Human))	BDBM46298 (2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[(3-methylbe...) Show SMILES Cc1cccc(C=NN(CCO)C2=NS(=O)(=O)c3ccccc23)c1 |w:7.7,t:12| Show InChI InChI=1S/C17H17N3O3S/c1-13-5-4-6-14(11-13)12-18-20(9-10-21)17-15-7-2-3-8-16(15)24(22,23)19-17/h2-8,11-12,21H,9-10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M61HPT
					More data for this Ligand-Target Pair
glutathione S-transferase (Homo sapiens (Human))	BDBM46298 (2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[(3-methylbe...) Show SMILES Cc1cccc(C=NN(CCO)C2=NS(=O)(=O)c3ccccc23)c1 |w:7.7,t:12| Show InChI InChI=1S/C17H17N3O3S/c1-13-5-4-6-14(11-13)12-18-20(9-10-21)17-15-7-2-3-8-16(15)24(22,23)19-17/h2-8,11-12,21H,9-10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.02E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZC8184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). (Homo sapiens (Human))	BDBM46298 (2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[(3-methylbe...) Show SMILES Cc1cccc(C=NN(CCO)C2=NS(=O)(=O)c3ccccc23)c1 |w:7.7,t:12| Show InChI InChI=1S/C17H17N3O3S/c1-13-5-4-6-14(11-13)12-18-20(9-10-21)17-15-7-2-3-8-16(15)24(22,23)19-17/h2-8,11-12,21H,9-10H2,1H3	PDB KEGG B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GH9GBT
					More data for this Ligand-Target Pair