null
SMILES: CC(C)N(C)c1nc2cc(ccc2nc1-c1ccc2nccn2c1)C(O)=O
InChI Key: InChIKey=WBPJYDOVOKDDEU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PAS domain-containing serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM463503 (2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC US Patent | Assay Description Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i... | US Patent US10781185 (2020) BindingDB Entry DOI: 10.7270/Q2DR2ZKW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAS domain-containing serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM463503 (2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D79FN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human)) | BDBM463503 (2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D79FN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAS domain-containing serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM463503 (2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC US Patent | Assay Description Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ... | US Patent US10781185 (2020) BindingDB Entry DOI: 10.7270/Q2DR2ZKW | |||||||||||
More data for this Ligand-Target Pair |