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SMILES: COc1ccc(cc1OC1CN(C1)c1ccc(cn1)C#N)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO

InChI Key: InChIKey=RIMCISMKSOSZMT-JLUIAWOOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463561   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM463561
PNG
((2S)-3-[(3S,4S)- 3-[(1R)-1- hydroxyethyl]-4- (4-me...)
Show SMILES COc1ccc(cc1OC1CN(C1)c1ccc(cn1)C#N)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO |r|
Show InChI InChI=1S/C26H32N4O6/c1-16(32)26(2)15-30(25(34)21(33)14-31)13-20(26)18-5-6-22(35-3)23(8-18)36-19-11-29(12-19)24-7-4-17(9-27)10-28-24/h4-8,10,16,19-21,31-33H,11-15H2,1-3H3/t16-,20+,21+,26+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.310n/an/an/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
 PDE4A, PDE4B, PDE4C, PDE4D, and PDE5 human recombinant proteins are expressed and purified from Saccharomyes cerevisiae that lack endogenous PDEs. T...

US Patent US10781202 (2020)


BindingDB Entry DOI: 10.7270/Q2571G2N
More data for this
Ligand-Target Pair