null

SMILES: COc1ccc(cc1)-c1nn(C[C@@H]2CC[C@H](COCC(O)=O)CC2)c(=O)nc1-c1ccccc1

InChI Key: InChIKey=GWKZBHISORWCRW-KDURUIRLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostacyclin receptor (Homo sapiens (Human))	BDBM464509 (2-(((1s,4s)-4-((6-(4- methoxyphenyl)-3-oxo-5- phen...) Show SMILES COc1ccc(cc1)-c1nn(C[C@@H]2CC[C@H](COCC(O)=O)CC2)c(=O)nc1-c1ccccc1 |r,wU:12.12,15.16,(-10,4.62,;-10,3.08,;-8.67,2.31,;-7.34,3.08,;-6,2.31,;-6,.77,;-7.34,,;-8.67,.77,;-4.67,,;-3.33,.77,;-2,,;-.67,.77,;.67,,;.67,-1.54,;2,-2.31,;3.33,-1.54,;4.67,-2.31,;6,-1.54,;7.34,-2.31,;8.67,-1.54,;10,-2.31,;8.67,,;3.33,,;2,.77,;-2,-1.54,;-.67,-2.31,;-3.33,-2.31,;-4.67,-1.54,;-6,-2.31,;-7.34,-1.54,;-8.67,-2.31,;-8.67,-3.85,;-7.34,-4.62,;-6,-3.85,)| Show InChI InChI=1S/C26H29N3O5/c1-33-22-13-11-21(12-14-22)25-24(20-5-3-2-4-6-20)27-26(32)29(28-25)15-18-7-9-19(10-8-18)16-34-17-23(30)31/h2-6,11-14,18-19H,7-10,15-17H2,1H3,(H,30,31)/t18-,19+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
ARENA PHARMACEUTICALS, INC. US Patent					Assay Description The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...				US Patent US10793529 (2020)
					More data for this Ligand-Target Pair