null

SMILES: OC(=O)COC[C@H]1CC[C@@H](Cn2nc(-c3ccccc3)c(nc2=O)-c2cccc(Cl)c2)CC1

InChI Key: InChIKey=TYIVBLXHCNPROI-HDICACEKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostacyclin receptor (Homo sapiens (Human))	BDBM464512 (2-(((1s,4s)-4-((5-(3- chlorophenyl)-3-oxo-6- pheny...) Show SMILES OC(=O)COC[C@H]1CC[C@@H](Cn2nc(-c3ccccc3)c(nc2=O)-c2cccc(Cl)c2)CC1 |r,wU:9.9,6.5,(9.34,-.77,;8,,;8,1.54,;6.67,-.77,;5.33,,;4,-.77,;2.67,,;1.33,-.77,;;,1.54,;-1.33,2.31,;-2.67,1.54,;-4,2.31,;-5.33,1.54,;-6.67,2.31,;-6.67,3.85,;-8,4.62,;-9.34,3.85,;-9.34,2.31,;-8,1.54,;-5.33,,;-4,-.77,;-2.67,,;-1.33,-.77,;-6.67,-.77,;-8,,;-9.34,-.77,;-9.34,-2.31,;-8,-3.08,;-8,-4.62,;-6.67,-2.31,;1.33,2.31,;2.67,1.54,)| Show InChI InChI=1S/C25H26ClN3O4/c26-21-8-4-7-20(13-21)23-24(19-5-2-1-3-6-19)28-29(25(32)27-23)14-17-9-11-18(12-10-17)15-33-16-22(30)31/h1-8,13,17-18H,9-12,14-16H2,(H,30,31)/t17-,18+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
ARENA PHARMACEUTICALS, INC. US Patent					Assay Description The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...				US Patent US10793529 (2020)
					More data for this Ligand-Target Pair