BDBM46900 4,5-Dichloro-isothiazole-3-carboxylic acid benzyl-[cyclopentylcarbamoyl-(4-methoxy-phenyl)-methyl]-amide::4,5-bis(chloranyl)-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxidanylidene-ethyl]-N-(phenylmethyl)-1,2-thiazole-3-carboxamide::4,5-dichloro-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(phenylmethyl)-3-isothiazolecarboxamide::MLS000552854::N-benzyl-4,5-dichloro-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-1,2-thiazole-3-carboxamide::N-benzyl-4,5-dichloro-N-[2-(cyclopentylamino)-2-keto-1-(4-methoxyphenyl)ethyl]isothiazole-3-carboxamide::SMR000173026::cid_3197152

SMILES: COc1ccc(cc1)C(N(Cc1ccccc1)C(=O)c1nsc(Cl)c1Cl)C(=O)NC1CCCC1

InChI Key: InChIKey=JBDRAQPCORIQNI-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 46900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
transient receptor potential cation channel, subfamily N, member 1 (Danio rerio)	BDBM46900 (4,5-Dichloro-isothiazole-3-carboxylic acid benzyl-...) Show SMILES COc1ccc(cc1)C(N(Cc1ccccc1)C(=O)c1nsc(Cl)c1Cl)C(=O)NC1CCCC1 Show InChI InChI=1S/C25H25Cl2N3O3S/c1-33-19-13-11-17(12-14-19)22(24(31)28-18-9-5-6-10-18)30(15-16-7-3-2-4-8-16)25(32)21-20(26)23(27)34-29-21/h2-4,7-8,11-14,18,22H,5-6,9-10,15H2,1H3,(H,28,31)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Z60MG3
					More data for this Ligand-Target Pair
MCOLN3 protein (Homo sapiens (Human))	BDBM46900 (4,5-Dichloro-isothiazole-3-carboxylic acid benzyl-...) Show SMILES COc1ccc(cc1)C(N(Cc1ccccc1)C(=O)c1nsc(Cl)c1Cl)C(=O)NC1CCCC1 Show InChI InChI=1S/C25H25Cl2N3O3S/c1-33-19-13-11-17(12-14-19)22(24(31)28-18-9-5-6-10-18)30(15-16-7-3-2-4-8-16)25(32)21-20(26)23(27)34-29-21/h2-4,7-8,11-14,18,22H,5-6,9-10,15H2,1H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21834W4
					More data for this Ligand-Target Pair